This horror film takes place in a prison hospital ward for those with mental disturbances. Maria de Guerra has been sent to prison to serve a life sentence because she killed her father when he tried to rape her. Maria is put in the mental ward when she arrives where torture, rape, and bestial violence are an everyday occurence. The Regional Governor comes to visit one day after receiving a letter from one othe prisoners describing the terrible events that go on. Maria and the other prisoners are unaware that the Governor is on the same side as the sadistic prison wardens. Maria and her new prison friends, Bertha and Rosario manage an escape after Maria seduces and kills Carlos Costa, a male nurse who was in love with her. The three hope to seek refuge at the Governor's home, unaware of his true nature.