Beautiful LYSISTRATA (Teyonah Parris) is in love with aspiring Rapper DEMTRIUS 'CHI-RAQ' DUPREE (Nick Cannon), but she is disturbed by the bloody war between his Spartan gang and the rival Trojans, led by CYCLOPS (Wesley Snipes). After Trojans set fire to her apartment while she's in bed with Chi-Raq (pronounced Shy-RACK), Lysistrata moves in with her neighbor MISS HELEN (Angela Bassett), a book-loving Peace activist who lost her daughter years before to a stray bullet. When Patti, an 11-year-old neighborhood girl, is accidentally killed in a drive-by shooting, her grieving mother IRENE (Jennifer Hudson) pleads with anyone who witnessed the crime to come forward. But even after a reward is offered by a local Church congregation led by fiery anti-gun-violence activist FR. MIKE CORRIDAN (John Cusack), no one is willing to identify the killer. Shaken by Patti's death and desperate to do something to stop the escalating bloodshed, Lysistrata persuades Spartan and Trojan women to swear off sex with their men until the fighting stops. To draw more attention to their cause, she leads the women in a bold occupation of a local armory, inspiring women across the city--and eventually the world--to join the boycott. As the ultimate battle of the sexes rages on, the city's fate hangs in the balance in this searing satire of gun violence in America.