Animated adventure starring Clifford the Big Red Dog. Clifford (voice of the late John Ritter) lives on Birdwell Island with his owner Emily Elizabeth Howard (Grey DeLisle). Even though he loves the Howards, Clifford starts to think that his enormous size is too much of a problem for them and, feeling unwanted, he runs off and joins the circus with his friends Cleo (Cree Summer) and T-Bone (Kel Mitchell). They fall in with a gang of other runaway animals, including a Chihuahua and a ferret. The dogs compete in a big contest in order to win a lifetime supply of Tummy Yummies.