Drama about four strangers (Julia Roberts, Jude Law, Natalie Portman and Clive Owen), their chance meetings, instant attractions and brutal betrayals. Dan (Jude Law) is a writer in London who wants to finish a novel, but in the meantime supports himself by writing obituaries. One day he meets Alice (Natalie Portman), a beautiful American and they immediately fall for each other. Dan initially returns her affection but soon her neediness begins to wear on him. Anna (Julia Roberts) is a photographer who is hired to take a portrait of Dan for the dust jacket of his book. Dan becomes attracted to her but she soon meets Larry (Clive Owen), a dermatologist, and marries him. Dan can't get Anna out of his mind even though she's married, and the two become lovers, but Dan is frustrated by the fact that Anna is reluctant to leave Larry for him.