Violent low-budget horror. Dr Timothy Straun (Andrew Divoff) is an ambitious medical researcher who is prepared to go to any lengths in his quest to design a revolutionary new drug to combat the impulses of rage in human beings. Straun uses homeless people and convicts in his experiments, and isn't averse to experimenting on himself. When Michael Dare (Stephen Polk) is arrested for a crime he didn't commit, he jumps at the chance to participate in Straun's research rather than go to jail. But after witnessing some strange goings-on, Michael teams up with surgeon Susan Verger (Denice Duff) to find out the truth behind the locked iron door that houses Dr Straun's sinsiter laboratory.