When Tex (Woody Allen) discovers his wife Candy (Sharon Stone) is having an affair with the local sheriff (Kiefer Sutherland), he murders her, chops her body into small pieces, and goes to dispose of them over the Mexican border. Trouble is, he's lost one of her hands and that hand has turned up - credited with the miraculous restoration of a blind woman's sight - as an object of local religious veneration. The mayor (Cheech Marin) sees an opportunity for profit and encourages the pilgrims and TV crews who are coming to witness the 'the hand of the Madonna'. Sensing that something is wrong, the village priest (David Schwimmer) and the local prostitute (Maria Grazia Cucinotta) raise their objections and set out to discredit the hand. Meanwhile, as the village descends into chaos, Tex must try to reclaim the hand himself, lest it be used as evidence against him.