Thriller set in the late 21st century. A vampire-like disease called hemophagia creates a subculture of genetically-modified humans. These humans have enhanced speed, incredible stamina and acute intelligence. As they are set apart from 'normal, healthy' humans, the world is pushed to the brink of worldwide civil war aimed at the destruction of the diseased population. In the middle of this crossfire is an infected woman, Ultraviolet (Milla Jovovich), who finds herself protecting a nine-year-old boy who has been marked for death by the human government as he is believed to be a threat to humans.