In Season 1, Wycliffe investigates the murder of a Penzance bookshop owner, the mysterious shooting of an archaeology student and the apparent suicide of an amateur flautist.
In Season 2, Wycliffe faces a race against time to recapture a dangerous escaped convict, investigates a suspected kidnapping and applies his professional know-how to a fatal shooting.
In Season 3, five bodies are discovered on an abandoned lorry at a ferry terminal, unexplained killings rock the Bodmin community and a murder victim is found buried with a cache of timber.
In Season 4, Wycliffe investigates bizarre events after the wedding of a couple, probes a fatal stabbing in a pub car park and looks into the mysterious disappearance of a yachtswoman.
In Season 5, Wycliffe searches for a prostitute's client before he kills again, a teacher is found murdered, a climber plunges to his death from a cliff face and a policeman is murdered.