Four animated adventures following the cheeky schoolboy Dennis. In 'Brother Rats', when Henry and George hold a fraternity reunion, Dennis mistakes two escaped convicts for 'frat brothers'. He invites them to join his fraternity, but the practical jokes that follow wind up making the pair wish they had never left jail. In 'Hospitality', Dennis goes into hospital, frightened by medical facts his friends have given. However, when Mr. Wilson accidentally winds up as his roommate, he forgets about his own fears, and sets out to protect his friend. 'It's A Guy Thing' sees Dennis decide he's too big for baby-sitters and tells Joey it's time they 'became men'. In 'Pains, Trains And Automobiles', Dennis wages an all-out commando strike on the neighbourhood bully. But he inadvertently 'captures' a toothache-ridden Mr. Wilson instead.