Documentary investigating how conceiving using a donor can affect families and individuals. 20-year-old JoEllen Marsh is eager to find her biological father, Jeffrey Harrison aka Donor 150. As her search gets underway JoEllen discovers she has a number of siblings living across the country. With the New York Times picking up her story, Jeffrey learns that she is looking for him and comes forward. The film follows JoEllen's journey to her meeting with Jeffrey and also explores evidence of biological connections, raising questions about nature and nuture, parenting, cryobanks and genetic inheritance.