Horror film, made as a pilot episode for a proposed TV series, very loosely based on the classic novel by Mary Shelley. For the past 200 years, brilliant and disturbed Dr. Victor Helios (Thomas Kretschmann) has kept himself and his masterpiece monster Deucalion (Vincent Perez) alive through his work in genetics. They have set up shop in New Orleans, where the Doctor has started a genome research institute and is planning on using his prototype to create a master race, which will eventually take over the Earth from conventionally produced humans. But Detective O'Connor (Parker Posey) is investigating the spate of gruesome murders that have plagued the city, and the trail leads her to the doctor. Meanwhile, Helios's tormented creations are becoming increasingly erratic in their behaviour.