Science fiction drama starring Jared Leto as a man looking back on his life. In the year 2092, 118-year-old Nemo Nobody (Leto) is an object of great interest - the last fully mortal human in a world where advances in technology have made immortality possible. Nemo is engaged in relating his life story to a journalist (Daniel Mays), but his mind appears to be failing. Nemo recounts at least three separate realities, one where he is married to a depressed woman, Elise (Sarah Polley), one where he enjoys a comfortable but boring life with Jean (Linh Dan Pham) and one where he is locked in a tempestuous romance with his step-sister, Anna (Diane Kruger). As the three stories unfold and interweave they ask questions, not just of the nature of memory, but of the nature of reality itself.