Spanish horror sequel in which another outbreak of a deadly infectious virus strikes an unsuspecting group of civilians. It is Koldo (Diego Martin) and Clara (Leticia Dolera)'s wedding day. Everything goes well, with the happy couple revelling in their special day, until an elderly guest who had complained of being bitten by a dog earlier in the day keels over and appears to be dead. However, subsequent events reveal that a fate far worse than death has struck the guest when he awakes and savagely bites his wife, triggering a further outbreak of the rabies-like infection among the wedding party. Amidst the chaos that ensues, Clara and Koldo become separated from one another. Can they find each other and make their escape before one of them becomes infected with the horrifying virus spreading like wildfire through the group?