Charlton Heston stars in this American sci-fi action feature. In 1977, the world's population has been virtually wiped out by a plague caused by biological warfare. The lone survivor in the deserted city of Los Angeles is scientist Dr. Robert Neville (Heston) who believes it is his duty to fight off the bloodthirsty mutants, calling themselves The Family, who roam the city's streets. However, this all changes when he is saved from The Family by a group of normal, young people, and begins to find himself attracted to their leader, Lisa (Rosalind Cash). Together, they try to develop a cure to the disease by duplicating Neville's original vaccine but find themselves in a constant battle with infected members of The Family.