The crew embark on a quest to discover the Farpoint Station's secret; they fall victim to a mysterious disease; and they travel to Ligon II to acquire a vaccine for a plague running rampant on another planet.
Counsellor Troi (Marina Sirtis) gives birth to an unusual child; Picard activates the Enterprise's auto-destruct system in a bid to thwart a sadistic alien; and Data uses the holodeck to assume the identity of Sherlock Holmes.
The crew are left in mortal danger when the main computer breaks down; Data faces a race against time to persuade a human colony to flee before alien invaders arrive; and a Federation planet requests help from the Enterprise.
Picard returns to his roots in France as he recuperates from his ordeal at the hands of the Borg; Data's reunion with his creator is disrupted; and Picard encounters a human child who has been adopted by aliens.
Picard is stranded on a planet; he is compelled to accept a stubborn officer's assistance; and the crew encounters a destructive force.
Picard searches for Data in 19th-century San Francisco; an officer with an irrational fear of the transporter beam finally overcomes his phobia; and the Lumerian ambassador is beamed aboard to mediate a dispute.